Planarizable Push‐Pull Probes with Sulfoximine‐Bridged Dithienothiophene Acceptors

Contrary to sulfides, sulfoxides or sulfones, sulfoximines have been mostly neglected in the design of fluorescent probes until recently. In this study, we elaborate systematically on sulfoximine acceptors flipper probes. Fluorescent flippers introduced as mechanosensitive image membrane order and tension. They consist twisted dithienothiophene dimers with sulfide sulfone bridges produce essential primary dipole coupled push-pull system. The objective study was replace acceptor by a series sulfoximines. This is intriguing synthetic challenge worthwhile because extra nitrogen substituent offers variability that attractive understand control performance new provide corroborative evidence for importance planarizable probe. Partitioning into differently ordered membranes positioning within these different shown correlate directly dramatically fluorescence lifetimes mechanosensitivity. Sufficient partitioning confirmed particularly important tension probe compression ground state. Compared conventional homolog, best has more red-shifted absorption emission maxima, longer lifetime cell membranes, larger difference upon application